Would you like to research a PhD on microcalcifications in vulnerable plaque formation and translation of novel insights into meaningful clinical interventions for this multi-faceted disease? Would you like to increase our current knowledge on vulnerable plaque formation and will boost European innovation in delivering cost-effective solutions to reduce the pressing burden of AMI on the elderly population? Would you like to start your career in a European training network of leading research universities and professionals from the industry and consulting sector?
INTRICARE is an EU-funded PhD network coordinated by CARIM, School for Cardiovascular Diseases of Maastricht University, The Netherlands. INTRICARE brings together three university partners from across Europe to recruit a group of 15 of the best ‘early’ researchers. The doctoral researchers will work together with senior researchers from across the network.
Each candidate will be employed at one of the three universities and enrolled in a local PhD programme, while at the same time being part of an integrated research team and research project at network level.
The starting date for all positions is between March 1, 2017 and March 1, 2018. The positions are full-time for 3 years.
A common research agenda
INTRICARE is shaped to address the urgent, unmet medical needs concerning vulnerable plaques and is guided by the academic and industrial demand for a new generation of entrepreneurial scientists that have the skills, expertise and know-how to expedite our understanding of early atherogenesis and translation thereof into concrete clinical interventions for prevention and therapy.
Individual PhD projects
ESR1: A failing resolution of inflammation in increased plaque instability: cause or consequence of microcalcifications, Karolinska Institutet (Stockholm, Sweden)
ESR2: Contribution of calcium crystals to non-canonical inflammatory protein secretion in platelets and endothelial cells, CARIM, Maastricht University (The Netherlands)
ESR3: Vascular smooth muscle cell phenotypic switching, CARIM, Maastricht University (The Netherlands)
ESR4: Chronic kidney disease (CKD)– a clinical model of premature vascular ageing, Karolinska Institutet (Stockholm, Sweden)
ESR6: The role of GLP-1 in the development of diabetic intimal and medial calcification, Universitätsklinikum Aachen (Germany)
ESR7: Vascular remodeling: Identification and characterization of novel vSMCs markers relevant to vascular remodeling, Karolinska Institutet (Stockholm, Sweden)
ESR8: Dissecting the cross-interaction between vascular micro-calcification and inflammation: a human systems biology approach, CARIM, Maastricht University (The Netherlands)
ESR9: Molecular and drug design to detect and target vascular microcalcification, CARIM, Maastricht University (The Netherlands)
ESR10: Investigation of plaque vulnerability using Hybrid PET/MR imaging of key aspects of plaque vulnerability in different vascular beds, CARIM, Maastricht University (The Netherlands)
ESR11: Hybrid 18F-sodiumfluoride (NaF) positron emission tomography (PET)/magnetic resonance imaging (MRI) for non-invasive identification of microcalcifications as marker of arterial plaque vulnerability in human carotid- and coronary arteries, Universitätsklinikum Aachen (Germany)
ESR12: Innovative platforms to generate fetuin-A based imaging agents for diagnosis and treatment of microcalcification, Universitätsklinikum Aachen (Germany)
ESR13: Targeting Extracellular Vesicles for diagnosis and treatment of vascular calcification, Karolinska Institutet (Stockholm, Sweden)
ESR14: Role of AT2 receptor in intimal calcification, CARIM, Maastricht University (The Netherlands)
ESR15: Modulating Vitamin K-dependent proteins targeting Vascular calcification, Universitätsklinikum Aachen (Germany)
INTRICARE’s ambitious and demanding training programme will require highly motivated ESRs, who will be required to perform above the average PhD student. The 15 PhD researchers will work together as an integrated team within a carefully designed research programme aimed at jointly developing state-of-the-art theory and methods.
We invite candidates with an MA degree from a recognized accredited institution with a strong academic record in (bio)chemistry, (bio)physics, biological or medical sciences or a related scientific field to apply.
In assessing the candidates, particular emphasis will be placed on originality and creativity of the proposal, academic qualifications, and the individual project’s fit within the overall research programme. Candidates must have excellent writing skills as well as English language skills. Teamwork will be given emphasis, as INTRICARE is looking for dynamic and enthusiastic candidates collaborating well with other members of a team.
Two specific eligibility conditions apply to this funding scheme, the Innovative Training Networks (ITN) of the Marie Sklodowska-Curie actions (MSCA) in the EU’s Horizon 2020 programme:
If it is not evident from the application that the above criteria are met, please include an explanation as part of your application.
Further details can be found in the European Commission's Participant Portal, where a number of Frequently Asked Questions (FAQ) are assembled.
Please make sure that the criteria specified in the individual calls are met. These may vary depending on local PhD programmes and admission procedures. Some general requirements apply and the following documents must be submitted as part of each individual application.
Please read the qualifications for the positions carefully. We will only consider those who meet the listed requirements.
Job offers will be made to the selected candidates by the end of April 2017
Start date of all positions is depending on local admission programmes